Pharmacoepidemiol Drug Saf
September 2014
Purpose: The potential impact of drug-related problems (DRP) on morbidity and mortality is a serious concern in hospitalized patients. This study aimed to design a risk score to identify patients most at risk of a DRP.
Methods: Data from patients admitted to a tertiary university hospital between January and August 2009 were used to design the risk score (training set).
Objective: To assess the effectiveness of a simplified therapy for very nonadherent patients who had previously failed with HAART.
Method: We performed a prospective open-label study of antiretroviral-experienced patients. Dosing schedule comprised (co-formulated) zidovudine, lamivudine, and abacavir bid.
Background And Objective: Our goal was to assess the main characteristics of cardiovascular disease in HIV-infected patients on highly active antiretroviral therapy (HAART).
Patients And Method: Retrospective analysis of the clinico-epidemiological characteristics of 16 HIV-infected patients treated with HAART who had suffered a cardiovascular event from a 1,459 patients' cohort.
Results: Clinical presentation of cardiovascular disease was an acute coronary syndrome in 12 cases, ischemic stroke in 2 and peripheral vascular disease in 2.
Objectives: To assess the effect of antiretroviral therapy (ART) adherence on survival in HIV-infected patients.
Design: Cohort study at a single hospital in Barcelona, Spain.
Methods: Data on HIV-infected patients older than 18 years of age who began ART during the period 1990 to 1999 were analyzed.
Objective: To assess the effectiveness of the simplified medication adherence questionnaire (SMAQ) in identifying non-adherent patients.
Design: Prospective observational study of adherence. The six-item SMAQ was developed.