Publications by authors named "Alexi A Grom"
Article Synopsis
- This study focuses on a newly identified autoinflammatory disease caused by mutations in a tRNA processing enzyme, particularly examining its clinical features, immune responses, and molecular mechanisms.
- In nine patients diagnosed with congenital sideroblastic anemia, significant genetic mutations were found, along with elevated inflammatory cytokines and notable cellular abnormalities.
- Treatment with a TNF inhibitor successfully reduced inflammation and improved patient outcomes, highlighting the importance of early molecular diagnosis for effective intervention.
