Publications by authors named "Alexey Shabunin"

Extraskeletal chondromas are rare benign neoplasms comprising mature hyaline cartilage. A distinctive feature of these tumors is that they develop in soft tissues away from bone and cartilage. Extraskeletal chondromas account for 1.

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Extra-gastrointestinal stromal tumors arising from the pancreas are extremely rare. To date, just over 30 cases have been described in the world literature. A clinical observation of a 67-year-old patient with dull epigastric pain and a large cystic solid neoplasm instrumentally identified as an extra-gastrointestinal stromal tumor of the head of the pancreas is presented.

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Liver failure in patients with obstructive jaundice is a significant contributor to mortality within this patient cohort. The exact mechanism and triggers of this occurrence are yet to be fully understood. With this in mind, our study aimed to assess the correlation between the urinary 6 β-OHC/C ratio and various biochemical parameters of liver function.

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Article Synopsis
  • * From 2017 to 2021, 12 patients each underwent PAIR and ablation procedures; results showed fewer complications and shorter hospital stays for ablation patients.
  • * The findings indicate that RFA and MWA are safer and more effective, with no relapses in the first year for ablation patients compared to a 25% relapse rate in those who had the PAIR procedure.
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The inflammatory myofibroblastic tumor, which was first described in 1939, is a rare neoplasm that accounts for 0.04%-0.7% of all lung neoplasms.

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Effective treatment and prevention of infections challenge management of patients with chronic lymphicytic leukemia (CLL). The COVID-19 pandemic resulted in the reduction of outpatient hospital visits as a part of non-pharmaceutical interventions that could affect the incidence of infectious complications. Study enrolled patients with CLL receiving ibrutinib or/and venetoclax who were observed at the Moscow City Centre of Hematology from 01 April 2017 to 31 March 2021.

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Gallbladder trauma is a rare medical emergency in abdominal surgery because of its anatomic location. Gallbladder injury occurs in only 1.9%-2.

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The heterogeneity of thoracic wall tumors often represents challenging clinical entities for surgeons due to diagnostic and treatment complexities. The primary tumors, metastases, or direct invasion from intrathoracic structures comprise almost half of all cases on average that are proved to be malignant. Surgery treatment usually leaves large chest defects that require further extensive reconstruction and multimodal management including radiotherapy and chemotherapy.

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Objective: This review article summarises the latest evidence for preventive central lymph node dissection in patients with papillary thyroid cancer taking into account the possible complications and risk of recurrence.

Background: Papillary thyroid cancer is the most frequent histological variant of malignant neoplasms of the thyroid gland. It accounts for about 80-85% of all cases of thyroid cancer.

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Article Synopsis
  • The study aims to evaluate six micro-RNAs as potential biomarkers for predicting resistance to P2Y12-inhibitors in patients with acute coronary syndrome.
  • Eighty patients treated with either ticagrelor or clopidogrel underwent genotyping to assess specific polymorphisms and measured expression levels of the six miRNAs, with results correlating to platelet reactivity.
  • The findings suggest that miR-29, miR-34, miR-126, miR-142, and miR-223 could serve as valuable biomarkers for identifying P2Y12-inhibitor resistance, potentially replacing traditional platelet reactivity tests.
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Adrenal gland incidentaloma (incidental - sudden, accidental) is a mass of the adrenal gland(s), accidentally detected by an instru-mental examination conducted for other reasons. The frequency of detection of this pathology based on computer tomography of the abdominal organs is 0.5%-2%.

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