Planetary Metronome as a Regulator of Lifespan and Aging Rate: The Metronomic Hypothesis.

A metronomic mechanism for the duration control of ontogenetic cycle periods of an animal is proposed. The components of the proposed metronomic system include the ventricular system of the brain, planet Earth as a generator of metronomic signals, and temporal DNA (tDNA) as a substrate that is epigenetically marked to measure elapsed time of ontogenesis. The metronomic system generates repetitive signals in the form of hydrodynamic disturbances in the cerebrospinal fluid (CSF).

Eco-crossover, or environmentally regulated crossing-over, and natural selection are two irreplaceable drivers of adaptive evolution: Eco-crossover hypothesis.

The existence of an environmentally regulated version of meiotic crossing-over, or eco-crossover, is proposed, and the main consequences of this hypothesis are considered. Eco-crossover is a key source of partially directed genetic diversity of eukaryotes. In stressful environment, it creates ecologically justified and topologically specific genetic changes, and hence phenotypic variability, with which the selection works.

Role of the Earth's Motions in Plant Orientation - Planetary Mechanism.

According to the proposed theory, the starch-rich particles (statoliths) help the plant to convert the signals from Earth's motions into the signals necessary for the plant to perceive its orientation relative to the gravity vector while moving freely because of inertia in the sensory cells (statocytes) of roots and stems. Motions of the Earth are never constant, which, in particular, refers to the so-called polar motions and oscillations of the planet's rotation axis. Statoliths at any given moment move in the cytoplasmic liquid of statocytes due to inertial motion initiated by the action of the Earth's movements, maintaining the trajectory set by the previous movement of the oscillating planet.

Chronographic theory of development, aging, and origin of cancer: role of chronomeres and printomeres.

It is supposed that the development and aging of multicellular animals and humans are controlled by a special form of the clock mechanism - a chronograph. The development of animals and their aging are interconnected by the program of the species lifespan that has been selected in the evolution of each species to fit the resources of its ecological niche. The theory is based on the idea about a controlled loss by the neurons in the brain of hypothetical organelles - chronomeres that represent themselves small DNA molecules, which are amplificates of the segments of chromosomal DNA.

Chronographic Theory of Development, Aging, and Origin of Cancer: Role of Chronomeres and Printomeres.

It is supposed that the development and aging of multicellular animals and humans are controlled by a special form of the clock mechanism - a chronograph. The development of animals and their aging are interconnected by the program of the species lifespan that has been selected in the evolution of each species to fit the resources of its ecological niche. The theory is based on the idea about a controlled loss by the neurons in the brain of hypothetical organelles - chronomeres that represent themselves small DNA molecules, which are amplificates of the segments of chromosomal DNA.