Publications by authors named "Alexey Kim"

Article Synopsis
  • The study investigates tuberculosis (TB) trends in Kazakhstan from 2014 to 2019, focusing on incidence, mortality rates, and survival factors using extensive health data.
  • It found that while TB incidence decreased significantly, overall mortality rates increased, with specific demographic patterns indicating higher risk in older adults, men, urban dwellers, and patients with HIV or diabetes.
  • The research emphasizes the need for targeted health interventions based on demographic risk factors and underlines the importance of utilizing administrative health records for better public health policy in Kazakhstan.
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Rheumatoid arthritis is a systemic inflammatory disorder primarily affecting joints but not limited to the joints alone. Extra-articular manifestations involve skin, ocular, gastrointestinal, pulmonary, cardiac, renal, neurological, and hematological systems. Among them, skin manifestations (20%) are most common, presenting as nodules on the extensor surfaces of the upper and lower extremities.

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Inflammatory bowel disease (IBD), comprising mainly Crohn's disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disease of the gastrointestinal tract. In recent years, a wealth of data has been accumulated demonstrating the complex interplay of many different factors in the pathogenesis of IBD. Among these are factors impacting the epithelial barrier function, including vessel and extracellular matrix (ECM) formation, the gut microbiome (e.

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Receptor tyrosine kinase EGFR usually is localized on plasma membrane to induce progression of many cancers including cancers in children (Bodey . 2005, 19:931-41), but it contains a nuclear localization signal (NLS) that mediates EGFR nuclear translocation (Lin et al. Nat Cell Biol.

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