Publications by Alexey I Bobruskin

Publications by authors named "Alexey I Bobruskin"

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Chemotherapy of glioblastoma in rats using doxorubicin-loaded nanoparticles.

Sebastian C J Steiniger Jörg Kreuter Alexander S Khalansky Igor N Skidan Alexey I Bobruskin

Int J Cancer

May 2004

Glioblastomas belong to the most aggressive human cancers with short survival times. Due to the blood-brain barrier, they are mostly inaccessible to traditional chemotherapy. We have recently shown that doxorubicin bound to polysorbate-coated nanoparticles crossed the intact blood-brain barrier, thus reaching therapeutic concentrations in the brain.

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