Publications by authors named "Alexei F Licea"
Article Synopsis
- Ovarian cancer is a major health threat, often diagnosed late when it spreads throughout the abdomen, highlighting the need for new treatment strategies.
- Researchers developed an artificial transcription factor (ATF) to enhance the expression of Maspin, a protein that helps suppress metastasis, in aggressive ovarian cancer cell lines.
- The study showed that using ATFs could effectively inhibit tumor growth and invasion in lab models, with promising implications for targeted therapies in advanced ovarian cancer.
PDI enzymes are oxidoreductases that catalyze oxidation, reduction and isomerization of disulfide bonds in polypeptide substrates. We have previously identified an E. histolytica PDI enzyme (EhPDI) that exhibits oxidase activity in vivo.
View Article and Find Full Text PDFNonylphenol is a metabolic intermediate from the microbial transformation of detergents used worldwide. While nonylphenol shows some acute toxicity, it is also able to mimic important hormones resulting in the disruption of several processes by interfering with the signals that control the overall physiology of the organism. The effect of the pollutant nonylphenol (NP) through the trophic chain was studied.
View Article and Find Full Text PDFThe physiological function of T lymphocytes can be modulated selectively by peptide toxins acting on Kv1.3 K(+) channels. Because Kv1.
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