Publications by authors named "Alexanndra J Heyert"
Article Synopsis
- Choline geranate (CAGE) is a new antiseptic material that is biocompatible and enhances the delivery of antibiotics through the skin.
- CAGE effectively eradicates biofilms of multidrug-resistant ESKAPE pathogens at low concentrations, outperforming standard topical antiseptics in both potency and speed of action.
- Molecular modeling studies suggest that CAGE disrupts bacterial membranes, revealing its mechanism of action as a potent antibiofilm agent.
The A. aeolicus intrinsically disordered protein FlgM has four well-defined α-helices when bound to σ28, but in water FlgM undergoes a change in tertiary structure. In this work, we investigate the structure of FlgM in aqueous solutions of the ionic liquid [C4mpy][Tf2N].
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