Publications by authors named "Alexandru Ciprian Visan"

Left atrial (LA) geometry and phasic functions are frequently impaired in non-ischaemic dilated cardiomyopathy (NIDCM). Cardiac magnetic resonance (CMR) can accurately measure LA function and geometry parameters. We sought to investigate their prognostic role in patients with NIDCM.

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Objectives: In young and middle-aged adults, there are three current options for aortic valve replacement (AVR), namely mechanical AVR (mechAVR), tissue AVR (biological AVR) and the Ross operation, with no clear guidance on the best option. We aim to compare the clinical effectiveness and cost-effectiveness of the Ross procedure with conventional AVR in young and middle-aged adults.

Methods: This is a systematic literature review and meta-analysis of AVR options.

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Aortic valve replacement is the gold standard for the management of patients with severe aortic stenosis or mixed pathology that is not amenable to repair according to currently available guidelines. Such a simplified approach may be suitable for many patients, but it is far from ideal for young adults considering emerging evidence demonstrating that conventional valve replacement in this cohort of patients is associated with inferior long-term survival when compared to the general population. Moreover; the utilisation of mechanical and bioprosthetic valves can significantly impact on quality and is linked to increased rates of morbidities.

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A 15-year-old patient with hypoplastic left heart syndrome underwent 3-stage palliation by the age of 3 years. He was later diagnosed with Loeys-Dietz syndrome. On follow-up imaging, the neoaorta was dilated at 50 mm in diameter.

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Synopsis of recent research by authors named "Alexandru Ciprian Visan"

  • - Alexandru Ciprian Visan's research focuses on the prognostic role of cardiac parameters in non-ischaemic dilated cardiomyopathy, emphasizing the significance of left atrial geometry and phasic function measured through cardiac magnetic resonance.
  • - His work also critically evaluates surgical options for aortic valve replacement in young adults, comparing the clinical and cost-effectiveness of the Ross procedure against conventional methods, highlighting the need for tailored approaches in this demographic.
  • - Visan's studies address the complexities of aortic valve diseases, particularly in young patients, discussing the limitations of conventional treatments and exploring the implications of surgical interventions on long-term outcomes and quality of life.