Publications by authors named "Alexandros Tousis"
Acute coronary syndrome due to a non-atherosclerotic, non-traumatic, or iatrogenic-induced spontaneous coronary artery dissection (SCAD) is a rare clinical condition that affects mostly young women of reproductive age. In this case, we present a 36-week-pregnant, 35-year-old G2P1 woman, with no previous medical history, who was admitted to our hospital with premature pre-labor contractions. During her hospitalization, she underwent a coronary artery percutaneous angiography revealing SCAD of the three coronary vessels, after an episode of acute-onset chest pain, tachypnea, EKG alterations, cardiac enzyme elevation, and bilateral pleural effusions.
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- - Drug-coated balloons have been evaluated for safety and effectiveness in treating coronary and peripheral artery disease, with this study focusing on a new everolimus-coated balloon (ECB) in a swine model.
- - Thirty-two swine arteries were tested over 90 days in four groups, comparing different drug dosages of the ECB and other balloon types for their impact on arterial health.
- - Results indicated that the ECB was safe and effective, with one dosage showing the best outcomes, suggesting that the amount of everolimus used could influence how well the balloon works in preventing artery narrowing.
Coronary angiography and percutaneous coronary intervention (PCI) procedural details in swine are similar to those performed to humans, since their heart and coronary anatomy closely resembles. However, only a few detailed descriptions of the procedure are available, containing notable differences. We present a feasible and reproducible protocol for percutaneous coronary interventions in porcine experimental models, utilizing ultrasound-guided femoral approach.
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