Publications by authors named "Alexandros Kantas"
Article Synopsis
- - Hepatocellular carcinoma (HCC) is a serious and increasingly costly cancer, but current international guidelines don't prioritize measuring alpha-fetoprotein (AFP) levels before treatment.
- - This study analyzed data from 92 HCC patients to investigate the prognostic significance of AFP levels and found that higher AFP levels correlated with larger tumors and poorer survival outcomes.
- - The results suggest that measuring AFP could be clinically useful, as patients with high AFP levels experienced significantly shorter median survival times, indicating that AFP levels could inform treatment decisions.
Article Synopsis
- ALPPS increases the ability to surgically remove advanced-stage intrahepatic cholangiocarcinoma (ICC), with a study revealing a high rate of R0 resections (85%) among participants.
- A total of 102 patients were analyzed, with improvements in severe complications and mortality rates over the study period, identifying insufficient future liver remnant (FLR2) as a key risk factor for complications.
- Overall survival was significantly better for patients treated with ALPPS compared to those receiving chemotherapy alone, although this benefit was not observed in patients with insufficient FLR2 or multifocal ICC.
Background: Impaired postoperative renal function is associated with increased morbidity and mortality after liver resection. The role of impaired renal function in the two-stage hepatectomy setting of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is unknown.
Methods: An international multicenter cohort of ALPPS patients captured in the ALPPS Registry was analyzed.
Intraoperative fluorescence angiography and cholangiography with indocyanine green (ICG) are increasingly used in routine hepatobiliary surgery. Its usage is manifold. It improves and facilitates navigation especially in minimal invasive and robotic surgery and therefore increases the safety of the surgical intervention.
View Article and Find Full Text PDFThe population of kidney transplant (KTx) recipients often has complex medical and immunological conditions. Surgical complications (SCs) contribute to the increasing morbidity and costs in these patients. We analyzed the risk factors for SC in 405 KTx patients treated using defined immunosuppressive regimens according to their clinical and immunological risk profile: (1) standard immunosuppression (SIS) with IL-2 receptor mAb, CNI, and (a) mycophenolic acid (MPA) or (b) mTOR inhibitor; and (2) more intense immunosuppression (IIS) with (a) ATG or (b) the additional use of plasma exchange and B- and T-cell-depleting agents.
View Article and Find Full Text PDFObjectives: The Hardman index, which has five variables, has been recommended as a predictor of outcome after open repair of ruptured abdominal aortic aneurysms (RAAAs). It has been reported that the presence of three or more variables is uniformly fatal. The aim of this study was to test the same model in an independent series of RAAA patients undergoing endovascular repair.
View Article and Find Full Text PDF