Publications by authors named "Alexandria Luo"

Background: Metabolic risk factors are a significant cause of global burden among adolescents and young adults, but there is a lack of attention to the burden attributable to these metabolic risk factors globally.

Aims: This study aims to provide comprehensive estimates of five important metabolic risk factors and the attributable disease burden in people aged 15-39 years from 1990 to 2021, based on the Global Burden of Disease Study (GBD) database.

Methods: Global total deaths and disability-adjusted life years (DALYs) were used to describe the burden attributable to five common metabolic risk factors, including high fasting plasma glucose (FPG), high low-density lipoprotein cholesterol (LDL-C), high systolic blood pressure (SBP), high body mass index (BMI), and kidney dysfunction, in adolescents and young adults.

View Article and Find Full Text PDF

Elbow joint rehabilitation presents a formidable challenge, underscored by the joint's complex biomechanics and high vulnerability to injuries and degenerative conditions. Despite the advancements in rehabilitative technology, current solutions such as rigid exoskeletons often fall short in providing the precision, flexibility, and customization needed for effective treatment. Although traditional robotic aids, such as rigid exoskeletons, help recover, they lack in providing sufficient flexibility, comfort, and easy customization with no need for complicated calculation and complex design considerations.

View Article and Find Full Text PDF

Overview of personalized dietary therapies. This flow chart exhibits the future prospect for integrating human microbiome and bio-medical research to revolutionize the precise personalized dietary therapies. With the development of artificial intelligence (AI), incorporating database may achieve personalized dietary therapies with high precision.

View Article and Find Full Text PDF
Observation of the decay.

Eur Phys J C Part Fields

October 2024

Using proton-proton collision data corresponding to an integrated luminosity of collected by the CMS experiment at , the decay is observed for the first time, with a statistical significance exceeding 5 standard deviations. The relative branching fraction, with respect to the decay, is measured to be , where the first uncertainty is statistical, the second is systematic, and the third is related to the uncertainties in and .

View Article and Find Full Text PDF
Article Synopsis
  • - Obesity is a major global health concern, with a significant rise in deaths and disability-adjusted life years (DALYs) linked to high body mass index (BMI) from 1990 to 2021, notably increasing by over 2.5 times for both genders.
  • - The main health issues associated with high BMI in 2021 included diabetes, heart disease, and stroke, with low-middle socio-demographic index (SDI) countries experiencing the largest increase in disease burden.
  • - The findings call for urgent monitoring and intervention efforts to address the growing health impact of high BMI from 1990 to 2021, especially given the stable death rates for women and rising rates for men.
View Article and Find Full Text PDF
Article Synopsis
  • Demand for computing power in major scientific experiments, like the CMS at CERN, is expected to significantly increase over the coming decades.
  • The implementation of coprocessors, particularly GPUs, in data processing workflows can enhance performance and efficiency, especially for machine learning tasks.
  • The Services for Optimized Network Inference on Coprocessors (SONIC) approach allows for improved use of coprocessors, demonstrating successful integration and acceleration of workflows across various environments without sacrificing throughput.
View Article and Find Full Text PDF

Background: Common metabolic diseases, such as type 2 diabetes mellitus (T2DM), hypertension, obesity, hypercholesterolemia, and metabolic dysfunction-associated steatotic liver disease (MASLD), have become a global health burden in the last three decades. The Global Burden of Disease, Injuries, and Risk Factors Study (GBD) data enables the first insights into the trends and burdens of these metabolic diseases from 1990 to 2021, highlighting regional, temporal and differences by sex.

Methods: Global estimates of disability-adjusted life years (DALYs) and deaths from GBD 2021 were analyzed for common metabolic diseases (T2DM, hypertension, obesity, hypercholesterolemia, and MASLD).

View Article and Find Full Text PDF

Introduction: The United Nation's Sustainable Development Goal (SDG) 6 calls for universal access to clean water, sanitation and hygiene (WASH), which are crucial elements of health and well-being and fundamental for a life in dignity. Early childhood caries (ECC) is a preventable disease affecting health and quality of life of millions of young children worldwide. This scoping review aims to explore the connection between ECC and access to clean water and sanitation.

View Article and Find Full Text PDF

A search for exotic decays of the Higgs boson () with a mass of 125 to a pair of light pseudoscalars is performed in final states where one pseudoscalar decays to two quarks and the other to a pair of muons or leptons. A data sample of proton-proton collisions at corresponding to an integrated luminosity of 138 recorded with the CMS detector is analyzed. No statistically significant excess is observed over the standard model backgrounds.

View Article and Find Full Text PDF

Background: Preoperative albumin-bilirubin (ALBI) grade has been proposed and applied in recent years to evaluate the prognosis of liver cancer, but its role in gastric cancer (GC) is still unclear. This research aimed to examine the prognostic value of ALBI grade after gastrectomy among patients with GC complicated with metabolic syndrome (MetS).

Methods: There were 628 patients who received radical resection for GC.

View Article and Find Full Text PDF

This study was a retrospective self-controlled study that aimed to evaluate the effect of arthroscopic discopexy on condylar height and mandibular position in adolescents with temporomandibular joint (TMJ) anterior disc displacement without reduction (ADDwoR). Patients between 10 and 20 years of age and diagnosed with bilateral TMJ ADDwoR by magnetic resonance image (MRI) were included in this study. All patients underwent a period of natural course before arthroscopic surgery and then a follow-up period postoperatively.

View Article and Find Full Text PDF

The mass of the top quark is measured in 36.3 of LHC proton-proton collision data collected with the CMS detector at . The measurement uses a sample of top quark pair candidate events containing one isolated electron or muon and at least four jets in the final state.

View Article and Find Full Text PDF

A search for decays to invisible particles of Higgs bosons produced in association with a top-antitop quark pair or a vector boson, which both decay to a fully hadronic final state, has been performed using proton-proton collision data collected at by the CMS experiment at the LHC, corresponding to an integrated luminosity of 138. The 95% confidence level upper limit set on the branching fraction of the 125 Higgs boson to invisible particles, , is 0.54 (0.

View Article and Find Full Text PDF

Multijet events at large transverse momentum () are measured at using data recorded with the CMS detector at the LHC, corresponding to an integrated luminosity of . The multiplicity of jets with that are produced in association with a high- dijet system is measured in various ranges of the of the jet with the highest transverse momentum and as a function of the azimuthal angle difference between the two highest jets in the dijet system. The differential production cross sections are measured as a function of the transverse momenta of the four highest jets.

View Article and Find Full Text PDF

The production of Z bosons associated with jets is measured in collisions at with data recorded with the CMS experiment at the LHC corresponding to an integrated luminosity of 36.3. The multiplicity of jets with transverse momentum is measured for different regions of the Z boson's , from lower than 10 to higher than 100.

View Article and Find Full Text PDF

Production cross sections of the standard model Higgs boson decaying to a pair of W bosons are measured in proton-proton collisions at a center-of-mass energy of 13. The analysis targets Higgs bosons produced via gluon fusion, vector boson fusion, and in association with a W or Z boson. Candidate events are required to have at least two charged leptons and moderate missing transverse momentum, targeting events with at least one leptonically decaying W boson originating from the Higgs boson.

View Article and Find Full Text PDF

The double differential cross sections of the Drell-Yan lepton pair (, dielectron or dimuon) production are measured as functions of the invariant mass , transverse momentum , and . The observable, derived from angular measurements of the leptons and highly correlated with , is used to probe the low- region in a complementary way. Dilepton masses up to 1 are investigated.

View Article and Find Full Text PDF

New sets of parameter tunes for two of the colour reconnection models, quantum chromodynamics-inspired and gluon-move, implemented in the pythia  8 event generator, are obtained based on the default CMS pythia  8 underlying-event tune, CP5. Measurements sensitive to the underlying event performed by the CMS experiment at centre-of-mass energies and 13, and by the CDF experiment at 1.96 are used to constrain the parameters of colour reconnection models and multiple-parton interactions simultaneously.

View Article and Find Full Text PDF

A measurement of the jet mass distribution in hadronic decays of Lorentz-boosted top quarks is presented. The measurement is performed in the lepton + jets channel of top quark pair production () events, where the lepton is an electron or muon. The products of the hadronic top quark decay are reconstructed using a single large-radius jet with transverse momentum greater than 400.

View Article and Find Full Text PDF

A search is reported for pairs of light Higgs bosons () produced in supersymmetric cascade decays in final states with small missing transverse momentum. A data set of LHC collisions collected with the CMS detector at and corresponding to an integrated luminosity of 138 is used. The search targets events where both bosons decay into pairs that are reconstructed as large-radius jets using substructure techniques.

View Article and Find Full Text PDF
Article Synopsis
  • * Researchers developed a novel monoclonal antibody (mAb) called "mAbtyrin" that targets multiple bacterial processes, enhancing its effectiveness against S. aureus.
  • * mAbtyrin showed improved protection in preclinical models, including better defense against infections and enhanced effectiveness when used with vancomycin, suggesting it could be a promising treatment for S. aureus-related diseases.
View Article and Find Full Text PDF

NLRP12 has dual roles in shaping inflammation. We hypothesized that NLRP12 would modulate myeloid cells and T cell function to control systemic autoimmunity. Contrary to our hypothesis, the deficiency of in autoimmune-prone B6.

View Article and Find Full Text PDF

Objectives: This study aims to identify existing reporting standards for child health research, assess the robustness of the standards development process, and evaluate the dissemination of these standards.

Study Design And Setting: We searched MEDLINE, the EQUATOR Network Library, and Google to identify reporting standards for child health research studies. We assessed the adherence of the Guidance for Developers of Health Research Reporting Guidelines (GDHRG) by the identified reporting standards.

View Article and Find Full Text PDF