Variants at the MHC Region Associate With Susceptibility to Infection: A Genome-Wide Association Study Using Comprehensive Electronic Health Records.

Background: is a major cause of healthcare-associated and community-acquired diarrhea. Host genetic susceptibility to infection has not been studied on a large-scale.

Methods: A total of 1,160 infection cases and 15,304 controls were identified by applying the eMERGE infection algorithm to electronic health record data.