Publications by authors named "Alexandre Nascimento"

This study aimed to describe the severity of abortion-related complications, factors associated with complications, the types of management and the experience of care in Brazil. A cross-sectional study in twenty hospitals (10 in Federal District, 3 in Rondônia and 7 in Maranhão). For 3 months, all women treated for abortion/miscarriage had their data collected.

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A paradigm shift in the understanding of bidirectional interactions between peripheral and central nervous systems is essential for development of rehabilitation and preventive interventions based on physical exercise. Although a causal relationship has not been completely established, modulation of voltage-dependent ion channels (Ca, Cl, K, Na, lactate-, H) in skeletal and neuronal cells provides opportunities to maintain force production during exercise and reduce the risk of disease. However, there are caveats to consider when interpreting the effects of physical exercise on this bidirectional axis, since exercise protocol details (e.

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Background: The original Latarjet-Patte procedure is a reliable technique to treat traumatic anterior shoulder instability. However, attempts to reduce possible complications have led to the emergence of modified techniques. More prominent among them are the arthroscopic approach and the use of cortical buttons for coracoid fixation.

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  • Developing new painkillers is tough because many potential drugs have serious side effects due to their impact on various biological pathways beyond just pain relief.
  • Researchers are focusing on targeting protein-protein interactions (PPIs) involved in pain signaling to create more effective and safer analgesics, using rodent models to evaluate their pain-reducing abilities.
  • By analyzing data from sensory nerve tissues, they identified key PPIs for exploring new drug designs, suggesting that blocking specific interactions in relevant proteins may improve pain treatment while minimizing unwanted effects.
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  • * This study aimed to compare how well the complement systems in humans and dogs can kill L. infantum, showing that human serum was more effective than dog serum.
  • * Although dog serum was generally less effective, infected dogs had a stronger immune response than non-infected ones, highlighting that dogs are more susceptible to visceral leishmaniasis than humans.
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Metabolic syndrome (MS) is a disorder that increasingly affects the world population, mainly because of changes in lifestyle and dietary habits. In this regard, both physical exercise and caffeine are low-cost and easily accessible therapies that separately have shown positive effects against metabolic disorders. Therefore, we hypothesized that physical exercise combined with caffeine could have a synergistic effect in the treatment of MS, risk factors, and cognitive deficits.

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Plant development and productivity depend on interactions with soil microorganisms for nutrient availability, promotion of growth and protection against phytopathogens. Although the influence of the phenological stages of soybean crops and their environmental conditions on the soil bacterial communities have already been reported, no studies have focused on the influence of integrated agrosilvopastoral systems on bacterial consortia. In this study, we evaluated the influence of the phenological stages of soybean cultivated under conventional full sunlight (CFS) and integrated crop-livestock-forestry (ICLF) systems on bacterial communities in the rhizosphere and in bulk soil using high-throughput sequencing techniques.

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Disruption of the blood-brain barrier and occurrence of coagulopathy after traumatic brain injury (TBI) have important implications for multiple secondary injury processes. Given the extent of post-traumatic changes in neuronal function, significant alterations in some targets, such thrombin (a protease that plays a physiological role in maintaining blood coagulation), play an important role in TBI-induced pathophysiology. Despite the magnitude of thrombin in synaptic plasticity being concentration-dependent, the mechanisms underlying TBI have not been fully elucidated.

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Escaping the complement system is an important step in the establishment of infections. Some pathogens have acquired the ability to inactivate the complement system to ensure successful infection. This has been observed in parasites from the genus Leishmania, which inactivate C3b molecules deposited on their surface through the membrane protease GP63.

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Introduction: The secretory breast carcinoma is very rare in children. It represents less than 1% of malignancy cases in childhood and is even less common in males, with 15 cases reported until 2004. Therefore, the aim of this study is to report a male child with breast carcinoma and review literature.

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Article Synopsis
  • The study assessed 20 patients who underwent reverse shoulder arthroplasty for rotator cuff arthropathy and evaluated their functional outcomes over an average follow-up of 42.4 months.
  • The patients displayed significant improvements in their post-operative scores across several metrics, including DASH, VAS, UCLA, and SF-36, indicating enhanced function and reduced pain levels.
  • While most patients reported good outcomes, some complications were noted, such as notching and one case of infection, but overall, the surgery substantially improved their quality of life.
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As most superhydrophobic coatings are made of soft materials, the need for harder, more robust films is evident in applications where erosional degradation is of concern. The work herein describes a methodology to produce superhydrophobic stainless-steel thermal spray coatings using the high-velocity oxygen fuel technique. Due to the use of a kerosene fuel source, a carbon-rich film is formed on the surface of the thermal spray coatings, lowering the surface energy of the high-energy metallic substrates.

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Complement inhibitors are present in all hematophagous arthropods. Lutzomyia longipalpis is an important vector of Leishmania infantum, the etiologic agent of visceral leishmaniasis in the Americas. Studies with this vector identified complement inhibitors and respective inhibitory mechanisms.

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Objective: To evaluate the outcomes of patients that underwent arthroscopic surgery for lateral epicondylitis (LE), after failed conservative treatment.

Methods: One hundred four patients with LE treated with arthroscopic debridement of the extensor carpi radialis brevis (ECRB) tendon were enrolled in this retrospective study. They were evaluated using Disabilities of the Arm, Shoulder and Hand (DASH) score, Visual Analogue Scale (VAS) and Short Form Health Survey (SF-36) scale.

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Objective: The cause of anterior shoulder instability is not fully understood and surgical management remains controversial. The objective of this study was to evaluate the results of patients undergoing arthroscopic Latarjet procedure with endobuttons.

Methods: A retrospective study of 26 patients undergoing arthroscopic Latarjet procedure with endobuttons to treat anterior shoulder instability.

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Objectives: To evaluate the results of patients undergoing arthroscopic surgical treatment for snapping scapula syndrome.

Methods: This is a retrospective study of 11 patients undergoing scapulothoracic arthroscopy for the treatment of snapping scapula syndrome. The study included patients with clinical diagnosis of snapping scapula syndrome who did not show pain improvement after at least six months of physical therapy.

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Measures of traits are the basis of functional biological diversity. Numerous works consider mean species-level measures of traits while ignoring individual variance within species. However, there is a large amount of variation within species and it is increasingly apparent that it is important to consider trait variation not only between species, but also within species.

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Background: The study purpose was to evaluate the outcomes of patients who received arthroscopic surgical treatment for medial epicondylitis refractory to conservative treatment.

Methods: This was a retrospective study of 7 patients who underwent arthroscopic surgical débridement of the common flexor tendon for treatment of medial epicondylitis refractory to conservative treatment. The patients were assessed using the Disabilities of the Arm, Shoulder and Hand score; visual analog scale for pain; and Short Form 36 Health Survey.

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Vegetated mounds are an important geomorphological feature of the Pantanal, where the influence of floods dictates not only hydropedological processes, but also the distribution and ecology of the flora and fauna. This work aimed to identify factors and processes that influence the formation and spatial distribution of the mounds, which are commonly associated with termite activity. In order to characterize pedological processes, macro and micro morphological descriptions, satellite image interpretation, dating of the sandy sedimentary material using OSL and carbon dating using 14C AMS were carried out.

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Snapping scapula syndrome has several etiologies, including subscapular osteochondroma. When this tumor needs to be removed, this can be done arthroscopically, a procedure that has restricted indications. The authors present a case of a patient with superomedial subscapular osteochondroma who underwent a scapulothoracic arthroscopy for its removal.

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Objective: To evaluate the results of patients undergoing arthroscopic surgical treatment of refractory lateral epicondylitis, identifying poor prognosis factors.

Methods: A retrospective study of 44 patients (47 elbows) who underwent arthroscopic debridement of the extensor carpi radialis brevis (ECRB) tendon to treat refractory lateral epicondylitis from February 2013 to February 2015, operated by a single surgeon at one center. Patients were assessed by DASH score, visual analog scale of pain (VAS), and ShortForm 36 (SF-36).

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Objective: To evaluate the use of magnetic resonance imaging (MRI) without contrast as a diagnostic method of partial lesions of the long head of the biceps, using arthroscopic surgery as the gold standard.

Methods: We evaluated data from MRI and arthroscopic surgical findings of patients operated due to rotator cuff and SLAP injuries. MRI without contrast of at least 1.

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Article Synopsis
  • A study evaluated the effectiveness of different surgical techniques for treating acromioclavicular joint dislocations (grades III and V), focusing on using anchors without eyelet and comparing them with alternatives like tightrope and cerclage.
  • Researchers analyzed 36 patients’ outcomes using various metrics (including DASH, UCLA, VAS, and SF-36) and noted that the average scores indicated good results across all techniques, with no significant difference in effectiveness.
  • The findings revealed that while using anchors without eyelet had a shorter average surgical time, the final radiological results were notably influenced by the initial spacing in the acromioclavicular joint and measurements taken post-surgery.
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Objective: To evaluate the clinical results among patients undergoing arthroscopic repair of circumferential labral lesions.

Methods: This was a retrospective study on 10 patients who underwent arthroscopic repair to circumferential labral lesions of the shoulder, between September 2012 and September 2015. The patients were evaluated by means of the Carter-Rowe score, DASH score, UCLA score, visual analog scale (VAS) for pain and Short-Form 36 (SF36).

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