Publications by authors named "Alexandre Nadeau"
Article Synopsis
- A national registry for congenital heart disease (CHD) in Canada aims to streamline research, cut costs, and enhance statistical power by automatically identifying CHD patients from existing clinical data.
- This project successfully extracted data from 885,287 echocardiogram reports and 70,121 clinical records, identifying over 43,000 children and nearly 5,000 fetuses with CHD.
- The initial registry in Québec demonstrates the potential for a centralized, user-friendly database that can support various CHD research projects and potentially expand to a national level.
Aims: Peripheral artery disease is a complication of diabetes leading to critical hindlimb ischemia. Diabetes-induced inhibition of VEGF actions is associated with the activation of protein kinase Cδ (PKCδ). We aim to specifically investigate the role of PKCδ in endothelial cell (EC) function and VEGF signaling.
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