Subepithelial connective tissue graft: an alternative application for treating endoperiodontal lesions.

This article presents an endoperiodontal lesion treated with a subepithelial connective tissue graft technique using periosteum. A patient with a right lateral maxillary incisor that had been retracted endodontically had gingival fenestration and recession, as well as an extensive apical lesion. Surgery was performed, and 5 months later a metal-ceramic crown was installed.

Human β-defensin 2 and protease activated receptor-2 expression in patients with chronic periodontitis.

Objective: Some previous studies have shown that gingipains, trypsin-like proteases produced by Porphyromonas gingivalis, up-regulate human β defensin-2 (HBD-2) mRNA expression through protease-activated receptor-2 (PAR(2)) in gingival epithelial cells. This study aimed at investigating salivary HBD-2 levels and crevicular PAR(2) mRNA expression in human chronic periodontitis and evaluating whether periodontal treatment affected this process.

Methods: Salivary and gingival crevicular fluid (GCF) samples were collected from periodontally healthy (control) and chronic periodontitis patients at baseline and 50 days after non-surgical periodontal treatment.