New Noninvasive Method for the Assessment of Central Venous Oxygen Saturations in Critically Ill Patients.

Objectives: To compare noninvasive external jugular vein oxygen saturations (SjvO) and central venous oxygen saturation (ScvO) from a blood sample in patients admitted to the intensive care unit.

Design: A prospective, comparative, monocentric clinical trial design was used.

Setting: The study was performed in the Department of Anaesthesiology, Pharmacology, Intensive Care and Emergency Medicine, University Hospitals of Geneva (Switzerland).

Informing Family About Patient Trajectory During Surgery: Design and Preliminary Evaluation.

The patient empowerment movement has highlighted the importance of providing information to the patients to improve care outcome. However, relatives of patients are not yet taken into consideration. This is especially problematic during surgeries since families are often left without real-time information about the trajectory of the patient, inducing worries.

Myocardial injury after major noncardiac surgery: A secondary analysis of a randomized controlled trial.

Background: Myocardial injury after noncardiac surgery frequently occurs and may influence survival. The aims of this study were to examine the association between myocardial injury after noncardiac surgery and patient and procedural factors as well as its impact on postoperative clinical outcome.

Methods: A retrospective analysis was conducted from data collected in adults enrolled in a randomized trial in elective major open abdominal surgery.

The hypoxic pulmonary vasoconstriction: From physiology to clinical application in thoracic surgery.

More than 70 years after its original report, the hypoxic pulmonary vasoconstriction (HPV) response continues to spark scientific interest on its mechanisms and clinical implications, particularly for anesthesiologists involved in thoracic surgery. Selective airway intubation and one-lung ventilation (OLV) facilitates the surgical intervention on a collapsed lung while the HPV redirects blood flow from the "upper" non-ventilated hypoxic lung to the "dependent" ventilated lung. Therefore, by limiting intrapulmonary shunting and optimizing ventilation-to-perfusion (V/Q) ratio, the fall in arterial oxygen pressure (PaO) is attenuated during OLV.