Phenotypic and genetic heterogeneity of in the course of an animal chronic infection.

is a nosocomial pathogen associated with various infections, including urinary tract infections (UTIs). In the course of an infection, is known to rapidly become resistant to antibiotic therapy, but much less is known about possible adaptation without antibiotic pressure. Through a retrospective study, we investigated within-host genetic diversity during a subclinical 5-year UTI in an animal-patient after withdrawal of colistin treatment.