Publications by authors named "Alexandre Bourgeois"
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Synopsis of recent research by authors named "Alexandre Bourgeois"
- Alexandre Bourgeois's recent research primarily focuses on the role of various protein fragments and enzymes in the pathology of diseases such as Alzheimer's and kidney disorders, particularly investigating mechanisms such as ectodomain shedding and mitochondrial dysfunction.
- Key findings include the involvement of metalloproteases ADAM10 and ADAM17 in the shedding of the phospholipase A2 receptor 1 (PLA2R1), which is crucial for autoimmune kidney diseases, and the intricate processing of amyloid precursor protein (APP) that contributes to Alzheimer's disease etiologies.
- His work also emphasizes the importance of early nutrition on the microbiota-gut-brain axis, suggesting that dietary choices can significantly impact development and health outcomes, as well as advancing methods to standardize electronic health data for broader research applications.
