Publications by authors named "Alexandra Wallem"
Introduction: To date, no study has compared the healthcare resource utilization (HCRU), costs, and discontinuation of the two calcitonin gene-related peptide antagonists, galcanezumab (monoclonal antibody subcutaneously injected monthly) and rimegepant (oral gepant taken every other day), for migraine prevention. This study aimed to assess all-cause and migraine-related HCRU, costs, and treatment discontinuation at 12 months following treatment initiation in commercial/Medicare beneficiaries with episodic migraine who received galcanezumab versus rimegepant as preventive migraine treatment.
Methods: This retrospective study used the Merative™ MarketScan Research Databases (June 2020-June 2023).
Objectives: To evaluate the use of a risk stratification tool and explore the contributing factors to variation in practice by clinical pharmacists.
Methods: The quantitative phase was a prospective evaluation of adherence to the risk stratification tool. Patients were selected by convenience sampling from medical wards across two hospital sites.
Racial Disparities in Nursing Home Resident and Staff COVID-19 Vaccination Rates.
J Health Care Poor Underserved
October 2022
Objectives: To determine whether staff and resident COVID-19 vaccination rates varied by racial heterogeneity of nursing homes, defined as proportion of residents who are White.
Methods: Cross-sectional study using data from the Medicare COVID-19 Nursing Home Database and LTCFocus.org to examine facility-level resident and staff vaccination status.
Objectives: This study examines the association between antipsychotic (AP) medication use and care transitions in the nursing home (NH) population.
Methods: This cross-sectional study used data from a 5% random sample of Medicare beneficiaries between 2011 and 2015. Propensity score adjusted negative binomial regression was performed and conditional probabilities of having a first transition from the NH to specific locations were calculated.
Background: There is currently insufficient data describing how new medications are provided to older adult ambulatory patients with dementia in the United States (US).
Objectives: To describe characteristics of ambulatory care visits for adults ≥65 years old and investigate differences in prescribing of new medications between patients with and without dementia.
Methods: We conducted a population-based cross-sectional study using the 2016 National Ambulatory Medical Care Survey (NAMCS) in the US.
Objectives: During the last quarter of 2020-despite improved distribution of personal protective equipment (PPE) and knowledge of COVID-19 management-nursing homes experienced the greatest increases in cases and deaths since the pandemic's beginning. We sought to update COVID-19 estimates of cases, hospitalization, and mortality and to evaluate the association of potentially modifiable facility-level infection control factors on odds and magnitude of COVID-19 cases, hospitalizations, and deaths in nursing homes during the third surge of the pandemic.
Design: Cross-sectional analysis.
Background: With the older adult population in the USA increasing, so is the population of those with Alzheimer's disease and related dementias (ADRD). Older adults are vulnerable to the effects of potentially inappropriate medications as established by the Beers Criteria; however, some medications continue to be prescribed against recommendations.
Objectives: Our objectives were to describe potentially inappropriate medication (PIM) use linked to cognitive impairment or decline (referred to as Cog-PIM) in older adults with and without ADRD and to investigate whether the odds of Cog-PIM report differ by ADRD status in ambulatory care (i.