Publications by authors named "Alexandra W Elias"
Article Synopsis
- The study explores the impact of primary tumor resection (PTR) and metastasectomy on survival in stage IV colon cancer patients, revealing mixed results.
- Out of 31,172 patients analyzed, those who underwent surgery had a median overall survival (OS) of 21.8 months, compared to 7.5 months for those who did not have surgery.
- Although both PTR and PTR with metastasectomy improved survival rates, there was no significant survival advantage for patients who underwent metastasectomy compared to those who only had PTR.
Background: Controversy exists regarding optimal surgical approach to right-sided colon cancer due to increasing complete mesocolic excision outcome data; yet, scarce long-term surgical and oncologic outcome data from high-volume centers following right segmental resections without complete mesocolic excision make comparisons difficult to interpret. We report long-term outcomes following standard mesocolic excision for right-sided colon adenocarcinoma.
Methods: A retrospective review of a prospective database was conducted of all consecutive adult patients undergoing surgery for a right-sided colon adenocarcinoma between 2000 and 2007.
Colonic small cell carcinomas (SCCs) are rare, aggressive tumors characterized by early metastasis and poor prognosis. We describe a 39-year-old man with a history of ulcerative colitis and left colon adenocarcinoma resected at an outside institution who presented with hematochezia and proctalgia. Work-up revealed left colon SCC with liver metastases.
View Article and Find Full Text PDFImmune checkpoint inhibitors (ICI) are revolutionizing care for cancer patients. The list of malignancies for which the Food and Drug Administration is granting approval is rapidly increasing. Furthermore, there is a concomitant increase in clinical trials incorporating ICI.
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