Publications by authors named "Alexandra Teodorescu"
Article Synopsis
- The study investigates how certain genes in Klebsiella pneumoniae are linked to the transition from gut colonization to infection, highlighting the genetic differences between strains.
- Researchers compared cases of infection (N=85) with asymptomatic carriers (N=160) to find 37 genes associated with infection risk, many related to stress and antibiotic resistance rather than traditional virulence factors.
- Five of these genes were further validated in a separate group, suggesting their role in understanding infection progression in patients carrying Klebsiella bacteria.
Article Synopsis
- Klebsiella is a common intestinal bacterium found in hospitalized patients and is a major contributor to health care-associated infections, with a notable risk for those who are colonized.* -
- A study tracked 1,978 patients who were colonized by Klebsiella for 90 days, revealing a 4.3% infection rate, with a mean infection onset of about 21 days; most infections originated from the same strain that colonized the patients.* -
- Factors such as overall health, depression, and low albumin levels at swab collection were linked to an increased risk of infection, suggesting that monitoring colonized patients could help prevent illness.*
RANKL (receptor activator of nuclear factor kappa- ligand) and OPG (osteoprotegerin) are two proteins involved in bone remodelling. During the active phase of periodontal disease, an imbalance between the ratios of the two elements can be noticed. While the expression of RANKL is elevated compared with that of OPG, the RANKL is available to bond with RANK (receptor activator of nuclear factor kappa-).
View Article and Find Full Text PDFThe present paper aims to highlight the role of arterial hypotension in the progression of glaucoma. The data analyzed in this study was collected in a prospective manner for a period of one year, from september 2013 to august 2014. It includes newly diagnosed glaucoma patients treated with prostaglandin analogues and who have presented within normal range values of intraocular pressure during the study.
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