Synopsis of recent research by authors named "Alexandra T Gast"
- Alexandra T Gast's research primarily explores the biochemical and functional characterization of enzymes, particularly topoisomerases, which play critical roles in DNA topology and cellular processes.
- In her 2014 study, she focused on the topoisomerase domain of Methanopyrus kandleri topoisomerase V, revealing its unique structural features and the arrangement of active site residues, contributing to the understanding of type IC topoisomerases.
- Her 2012 research involved the SRS gene superfamily in Toxoplasma gondii, identifying SRS29C as a negative regulator of virulence, demonstrating the importance of bioinformatics in elucidating the evolutionary and functional aspects of gene families.
