Stereotactic body radiation therapy effectively targets lung tumors with high doses in small areas, but the effects on surrounding tissues need to be closely monitored.
Researchers developed a mouse model to study the impact of deleting HIF-1α in endothelial cells on radiation-induced lung damage.
While the model showed promise for long-term study and reduced acute lung edema with HIF-1α deletion, it did not significantly improve long-term lung damage outcomes.