Publications by authors named "Alexandra Schulte"
A 19-year-old male presented to the emergency department with progressive right eye proptosis and was subsequently diagnosed with bacterial orbital cellulitis and acute on chronic allergic fungal sinusitis. He experienced brief symptomatic improvement after endoscopic sinus surgery, initiation of antibiotics, and steroid treatment; however, he re-presented five days after discharge with significantly worsened symptoms and no light perception in the right eye. Cultures resulted in Aspergillus and , a rare, aggressive etiology of bacterial orbital cellulitis.
View Article and Find Full Text PDFPurpose: To describe a case of non-arteritic ischemic optic neuropathy (NAION) secondary to Posner-Schlossman syndrome in a twenty-six-year-old female.
Observations: A 26-year-old female presented with painful visual loss of the left eye, elevated intraocular pressure of 38 mmHg, and trace to 1+ anterior chamber cell. Diffuse optic disc edema in the left eye and a small cup-to-disc ratio of the right optic disc were evident.
Dermal exposure and hair dye: Assessing potential bladder cancer risk from permanent hair dye.
Regul Toxicol Pharmacol
February 2023
Article Synopsis
- Hair dye products contain various chemicals, with para-phenylenediamine (PPD) being a common compound used to create a permanent effect; 4-aminobiphenyl (4-ABP) is often a trace contaminant associated with PPD and has been labeled a carcinogen by several regulatory agencies.
- The Office of Environmental Health Hazard Assessment (OEHHA) determined a cancer risk value for 4-ABP based on animal studies, and estimates of daily exposure to 4-ABP from hair dye application ranged dramatically, suggesting varying levels of risk.
- The findings indicate that there's no significant increased risk of bladder cancer for consumers using permanent hair dye with 4-ABP, particularly because the likelihood
The exceptional physical and chemical properties of nickel nanomaterials have been exploited in a range of applications such as electrical conductors, batteries, and biomaterials. However, it has been suggested that these unique properties may allow for increased bioavailability, bio-reactivity, and potential adverse health effects. Thus, the purpose of this review was to critically evaluate data regarding the toxicity of oxidic nickel nanoparticles (nickel oxide (NiO) and nickel hydroxide (Ni(OH)) nanoparticles) with respect to: (1) physico-chemistry properties; (2) nanomaterial characterization in the defined delivery media; (3) appropriateness of model system and translation to potential human effects; (4) biodistribution, retention, and clearance; (5) routes and relevance of exposure; and (6) current research data gaps and likely directions of future research.
View Article and Find Full Text PDFArticle Synopsis
- The study analyzed multidrug-resistant organisms (MDRO) found in ophthalmic cultures at Brooke Army Medical Center to understand treatment approaches and impact on vision.
- Of the 31 samples from 29 patients, a majority (72%) were methicillin-resistant Staphylococcus aureus (MRSA), with significant bacteria also found in corneal infections and adjustments often needed in antibiotic treatment.
- Despite treatments, many patients experienced stable or improved visual acuity, yet some still had poor outcomes (final acuity below 20/200), highlighting the need for further research into the visual impacts of MDRO in ophthalmic cases.