Publications by authors named "Alexandra S Bogdanova"
Article Synopsis
- The study explores using lytic bacteriophages combined with the antibiotic linezolid to treat methicillin-resistant bacteria, showing a strong synergistic effect against planktonic cells.
- A checkerboard assay indicated that a specific combination of low doses of both agents completely inhibited bacterial growth, but the order of treatments affected biofilm cells—sequential treatment was less effective while simultaneous treatment was more beneficial.
- Transcriptomic analysis revealed that the combination altered bacterial metabolism, including energy and virulence factors, emphasizing the need to optimize treatment strategies for maximum effectiveness against infections.
The morphology and proliferation of eukaryotic cells depend on their microenvironment. When electrospun mats are used as tissue engineering scaffolds, the local alignment of the fibers has a pronounced influence on cells. Here we analyzed the morphology of the patterned mats produced by electrospinning of PLA-gelatin blend onto a conductive grid.
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