The relationship between distortion product otoacoustic emissions and audiometric thresholds in the extended high-frequency range.

Distortion product otoacoustic emissions (DPOAEs) and behavioral audiometry are routinely used for hearing screening and assessment. These measures provide related information about hearing status as both are sensitive to cochlear pathologies. However, DPOAE testing is quicker and does not require a behavioral response.

Hearing outcomes in children with Congenital Cytomegalovirus: A multi-center, single-enterprise experience.

Background: Cytomegalovirus (CMV) is the most common cause of non-genetic sensorineural hearing loss (SNHL) in the United States; yet screening for congenital CMV (cCMV) remains controversial. CMV related SNHL can be present at birth, or develop in a delayed manner, and it is a consistent feature in children with either symptomatic or asymptomatic disease. A retrospective chart review was performed to determine the characteristics of patients diagnosed with cCMV and SNHL.

Cross-species experiments reveal widespread cochlear neural damage in normal hearing.

Animal models suggest that cochlear afferent nerve endings may be more vulnerable than sensory hair cells to damage from acoustic overexposure and aging. Because neural degeneration without hair-cell loss cannot be detected in standard clinical audiometry, whether such damage occurs in humans is hotly debated. Here, we address this debate through co-ordinated experiments in at-risk humans and a wild-type chinchilla model.

Individualized Assays of Temporal Coding in the Ascending Human Auditory System.

Neural phase-locking to temporal fluctuations is a fundamental and unique mechanism by which acoustic information is encoded by the auditory system. The perceptual role of this metabolically expensive mechanism, the neural phase-locking to temporal fine structure (TFS) in particular, is debated. Although hypothesized, it is unclear whether auditory perceptual deficits in certain clinical populations are attributable to deficits in TFS coding.