Concentrations of per- and polyfluoroalkyl substances (PFAS) in paired tap water and blood samples during pregnancy.

Abstract: Per- and polyfluoroalkyl substances (PFAS) are water-soluble chemicals of concern due to their persistence, ubiquity, and toxicity. We explored correlations between drinking water and blood PFAS levels in a subset of the mother-child Barcelona Life Study Cohort (BiSC), Barcelona, Spain (2021). For 105 study participants, we analyzed 35 PFAS in tap water (unfiltered and filtered) and 23 PFAS in 98 paired plasma samples during the 3rd trimester, using LC-MS/MS.