Sentinel lymph node metastasis in primary cutaneous basosquamous carcinoma. A cross-sectional study.

Background And Objectives: Basosquamous carcinoma (BSC) is a rare, biologically aggressive tumor. This cross-sectional study aims to define risk factors for subclinical nodal metastasis in primary BSC, and identify the patients who would benefit from routine sentinel node biopsy (SLNB) as part of the initial management.

Methods: A total of 142 patients, with histologically proven BSC without palpable lymph nodes, underwent SLNB after the initial excision.

Intranuclear Helioid Inclusions in a Case of Breast Carcinoma.

Helioid inclusions are single membrane-bounded intranuclear bodies of unknown nature which have been described in a case of breast adenoma, in mammary hyperplasia, and in a case of acinic cell carcinoma of the parotid gland. We report the detection of helioid inclusions in a case of breast carcinoma, which involves a 60-year-old woman with infiltrating ductal breast carcinoma of apocrine type. On electron microscopic examination we observed characteristic intranuclear helioid inclusions in some carcinoma cells.