Publications by authors named "Alexandra N McMahon"
Metabolomics in Radiotherapy-Induced Early Adverse Skin Reactions of Breast Cancer Patients.
Breast Cancer (Dove Med Press)
July 2024
Article Synopsis
- Early adverse skin reactions (EASRs) from radiotherapy can reduce the quality of life for breast cancer patients, and this study used metabolomics to identify related metabolic pathways and biomarkers.
- Researchers analyzed urine samples from 60 breast cancer patients (30 with high EASRs and 30 with low EASRs) to pinpoint significant metabolic pathways linked to these skin reactions before radiotherapy.
- The study found seven important metabolic pathways associated with EASRs, notably highlighting the alanine, aspartate, and glutamate metabolism pathway, suggesting that larger future studies could help develop targeted interventions to reduce these side effects.
Objectives: Patient-reported outcomes are critical to evaluate the effectiveness of medical cannabis as an alternative treatment for chronic pain. This study examined the perceived effectiveness of medical cannabis for chronic pain management among middle-aged and older adults newly initiating medical cannabis.
Methods: Interview data from participants in a three-month pilot study were analyzed to assess the perceived effectiveness of medical cannabis on chronic pain and related outcomes.