Publications by authors named "Alexandra Marley"
Crossing barriers: the burden of inflammatory bowel disease across Western Europe.
Therap Adv Gastroenterol
December 2023
An estimated 2.5-3 million individuals (0.4%) in Europe are affected by inflammatory bowel disease (IBD).
View Article and Find Full Text PDFIron deficiency anaemia: pathophysiology, assessment, practical management.
BMJ Open Gastroenterol
January 2022
Article Synopsis
- The WHO identifies iron deficiency anaemia (IDA) as the most prevalent nutritional deficiency globally, affecting 30% of people, mainly due to factors like gastrointestinal bleeding, menstruation, poor diet, and low iron absorption.
- Treatment for IDA focuses on replenishing iron levels and restoring normal haemoglobin, which can enhance quality of life and improve health outcomes in chronic diseases and pregnancy.
- The article covers updated strategies for diagnosing and managing IDA in patients with chronic conditions and during pregnancy, comparing oral and intravenous iron treatments, along with a cost analysis of various iron supplements.
Objective: Vitamin A (VA) deficiency, more common in low- and middle-income countries (LMIC) secondary to malnutrition, is associated with increased morbidity and mortality. The prevalence and impact of VA deficiency in high-income countries (HIC) where chronic conditions may predispose is less well understood.
Design: Interpretation of serum retinol may be affected by inflammation, so C-reactive protein (CRP) levels were sought.
Background: South Asians presenting with chest pain in the UK experience disproportionately greater delays with respect to diagnosis and treatment for acute myocardial infarction (AMI). The duration of time between symptom onset and hospital intervention is a critical delay for AMI but there are limited data amongst South Asians. The objectives of this study were to investigate ethnic differences in hospital delay and to look at short-term outcomes in South Asian and White patients presenting with AMI.
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