Changes in individual polycystic ovary syndrome phenotypical characteristics over time: a long-term follow-up study.

Objective: To assess the effects of aging on the features of polycystic ovary syndrome (PCOS).

Design: Cohort study.

Setting: Tertiary care center.

Improvements in PCOS characteristics and phenotype severity during a randomized controlled lifestyle intervention.

Research Question: What is the effect of weight loss through different interventions (three-component lifestyle intervention with short message service [SMS+] versus three-component lifestyle intervention without SMS [SMS-] versus care as usual [CAU]) on polycystic ovary syndrome (PCOS) characteristics (ovulatory dysfunction, hyperandrogenism, polycystic ovarian morphology [PCOM]) and phenotype distribution?

Design: Analysis of secondary outcome measures of a randomized controlled trial. Women diagnosed with PCOS (n = 183), who wished to become pregnant, with a body mass index above 25 kg/m², were assigned to a 1-year three-component (cognitive behavioural therapy, diet, exercise) lifestyle intervention group, with or without SMS, or to CAU (advice to lose weight).

Results: The prevalence of biochemical hyperandrogenism was 30.