Publications by authors named "Alexandra Kinzer"
Background: The objective of this meta-analysis was to examine the effectiveness of keloid intralesional excision (KILE) in preventing recurrence. Treatment of keloids using surgical excision alone leads to high rates of recurrence. To date, there are no widely accepted guidelines for keloid treatment, and a multitude of adjunctive therapies are used to reduce recurrence.
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- The study assesses the long-term survival and outcomes of liver transplant patients who required temporary abdominal closure versus those who had primary fascial closure, using data from 2013 to 2017 with a 5-year follow-up.
- Among 436 liver transplants, 17.2% needed temporary closure, which was associated with higher preoperative sickness (like higher MELD scores and more dialysis), and these patients also experienced longer hospital stays and higher readmission rates within 30 days.
- While initial 1-year survival rates were lower for those with temporary closure (82.7% vs 90.9%), 5-year survival rates were not significantly different, indicating that temporary closure is a safe alternative with comparable long-term
Context: Insulin resistance (IR) is associated with polycystic ovaries and hyperandrogenism, but underpinning mechanisms are poorly understood and therapeutic options are limited.
Objective: To characterize hyperandrogenemia and ovarian pathology in primary severe IR (SIR), using IR of defined molecular etiology to interrogate disease mechanism. To extend evaluation of gonadotropin-releasing hormone (GnRH) analogue therapy in SIR.
Black mothers in the United States have shorter breastfeeding (BF) durations and less exclusive breastfeeding (EBF) than others. The factors underlying these disparities require investigation. Using longitudinal data from a CDC-sponsored birth cohort in Cincinnati, Ohio, we analyzed the factors mediating racial disparity in BF outcomes.
View Article and Find Full Text PDFContext: Patients with lipodystrophy have dyslipidemia and insulin resistance. Leptin treatment with metreleptin in lipodystrophy decreases insulin resistance and lowers triglycerides without changing high-density lipoprotein. Detailed measurement of lipoprotein particles with nuclear magnetic resonance (NMR) spectroscopy can offer insights into cardiovascular disease (CVD) risk and lipid metabolism beyond a standard lipid panel.
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