Publications by authors named "Alexandra I Tokatly"
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Synopsis of recent research by authors named "Alexandra I Tokatly"
- Alexandra I Tokatly's research focuses on the synthesis, conformational analysis, and biological implications of sulfated carbohydrates, specifically exploring how modifications like sulfation influence the structural properties of glycosides and polysaccharides
- Findings from her studies indicate that varying sulfation patterns and stereochemical configurations of sugars, such as α-L-iduronopyranosides and D-glucuronic acid derivatives, significantly affect their conformational behavior, which may impact their biological functions and applications
- Tokatly's investigations into natural polysaccharides, particularly fucoidans from marine sources and their potential anti-tumor properties, highlight the challenges in translating experimental efficacy into clinical applications, emphasizing the need for further research in this area
