* A total of 7,435 studies were analyzed, with 50 papers meeting specific eligibility criteria, revealing a diversity in trial designs and intervention types, including multimodal approaches and various QOL measurement tools.
* Among the findings, 18 trials reported statistically significant improvements in QOL for intervention groups, highlighting the effectiveness of specific methods like the EORTC QLQ-C30 and FACIT questionnaires in evaluating patient outcomes.