Between a rock and a hard place: management of systemic lupus erythematosus and porphyria cutanea tarda.

Porphyria cutanea tarda (PCT), the most common porphyria, is a rare photodermatosis characterized by fragile, hemorrhagic bullae and erosions with associated milia, hyperpigmentation, and hypertrichosis. SLE is a systemic connective tissue disease with approximately 80% of those affected manifesting cutaneous findings. These include malar and discoid rashes, photosensitivity, bullae, oral ulcerations, as well as a variety of other nonspecific findings.

4-Day evaluation of the irritation potential of topical desoximetasone 0.25% and 0.05% spray on light-exposed skin.

Purpose: The safety and potential side effects of desoximetasone 0.25% and 0.05% sprays have not previously been studied.

Skin indentation firmness and tissue dielectric constant assessed in face, neck, and arm skin of young healthy women.

Purpose: Our goal was to test the hypothesis that skin firmness correlates with skin hydration.

Methods: Dermal water was assessed by tissue dielectric constant (TDC) at 0.5 mm (TDC ) and 2.

Age-related changes in male forearm skin-to-fat tissue dielectric constant at 300 MHz.

Prior research suggests that tissue dielectric constant (TDC) values are useful to assess localized skin water in females for early diagnosing breast cancer treatment-related lymphoedema and TDC values in young adults have shown gender differences. However, no TDC data are available for older males nor have ageing effects been studied despite known shifts in water state and other skin age-related changes. Thus our goals were to (i) characterize TDC values at various skin depths in young and older males, (ii) determine the dependence of these values on body composition parameters and (iii) establish inter-arm TDC ratios for use as normal male reference values.