Publications by authors named "Alexandra Goldshtein"
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Synopsis of recent research by authors named "Alexandra Goldshtein"
- Alexandra Goldshtein's recent research focuses on the impact of germline BRCA pathogenic variants on treatment outcomes in patients with locally advanced triple-negative breast cancer (TNBC) undergoing platinum-based neoadjuvant chemotherapy.
- The study utilizes a retrospective two-center cohort design, analyzing data from women with early-stage TNBC who completed genetic testing and underwent a specific chemotherapy regimen.
- Findings from the research aim to clarify the prognostic significance of gBRCA variants in TNBC and their potential role in informing treatment decisions for patients in the neoadjuvant setting.