Publications by authors named "Alexandra G Castillejos"

The Boston Keratoprosthesis type I (KPro-I) has been shown to be successful in restoring vision after severe ocular burns; however, its long-term outcomes in phthisical eyes have rarely been reported. A monocular woman with a history of severe alkali chemical injury necessitating facial transplantation presented with a light perception left eye after a complicated course, including failed KPro-I, therapeutic penetrating keratoplasty, endophthalmitis, hypotony, total retinal detachment, and structural changes, including a shrunken 18 mm axial length and eye wall thickening. The patient underwent a combined vitrectomy with silicone oil and KPro-I implantation, resulting in her regaining ambulatory visual acuity (20/250) at 3 years' follow-up

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Article Synopsis
  • This study investigates the effectiveness of Optical Coherence Tomography (OCT) imaging for evaluating glaucoma in patients with Boston keratoprosthesis (KPro) by assessing the quality and artifacts of retinal nerve fiber layer scans.
  • It found that a significantly higher percentage of KPro patients (40%) had poor signal strength in their OCT images compared to controls (5.3%), indicating challenges in obtaining quality images for glaucoma evaluation.
  • The results also revealed that only 43.1% of KPro patients had useful OCT scans for glaucoma assessment, and these patients tended to have better visual acuity and were less likely to have congenital corneal issues.
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Background: Radium-223 is used for the treatment of osseous metastases in castrate-resistant prostate cancer, and has been shown to increase time to the first skeletal-related event, reduce the rate of hospitalization, and improve quality of life. It is well tolerated, with hematologic toxicity as the main adverse event. Thus far, no ocular complication has been reported in the literature after initial administration of radium-223 with a single case reported of ocular complications after a patient's second course of radium-223.

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Purpose: To evaluate the safety and 1-year effect of pattern scanning laser photocoagulation treatment for pedunculated papillomatous and sessile conjunctival lesions in a low-resource setting with extremely limited operating room access.

Methods: Adult patients with clinical diagnosis of conjunctival papilloma underwent complete ophthalmologic exam including anterior segment photography. After topical anesthesia and toluidine blue 1% instillation, the lesion was treated by pattern scanning photocoagulation using a duration time that varied from 20 to 100 ms and power from 600 to 1800 mW, treating the entire lesion surface with a 2 mm margin.

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