Effects of the simultaneous use of drug-eluting stents and statins in an atherosclerotic animal model.

Introduction: The use of statins and medicated stents (MS) is the best available therapy for the treatment of severe coronary disease in selected cases. However, the vascular effects of the simultaneous use of both therapies are unknown.

Materials And Methods: An experimental study was carried out on 60 NZ rabbits with advanced atherosclerosis, distributed in four groups of 15 animals each.

The role of potassium channels in the vasodilatory effect of caffeine in human internal mammary arteries.

There is little information about the direct effect of caffeine in human blood vessels. The purpose of this study was to evaluate the direct vascular effect of caffeine on human internal mammary artery (IMA) and the involvement of potassium channels in this response. Segments of IMA were obtained from 29 patients who underwent coronary artery bypass graft surgery.

[In vitro effect of caffeine on internal mammary artery rings used in cardiac revascularization surgery].

Introduction: The vasodilator effect of caffeine in animal models arteries has been demonstrated previously. However, studies with the same methodology using human arteries in vitro have not been performed.

Objectives: The in vitro vasoactive effects of caffeine was evaluated on human internal mammary arteries.