Publications by authors named "Alexandra Csenkey"
Background: There are several options available for conservative treatment of partial-thickness burns, however, reliable, affordable, and easily obtainable animal testing models are hard to find for the comparison of the different treatment methods. We aimed at developing a preclinical testing model and at comparing four treatment methods for superficial partial-thickness burns.
Methods: Burn injury was induced in 90 adult male Wistar rats by placing the 130°C hot tip of a commercially obtainable soldering device for 30 s on the clipped skin of the interscapular region at a steady pressure.
Article Synopsis
- Noninvasive ventilation (NIV) shows promise in reducing mortality and intubation rates in adults with pneumonia-associated respiratory failure compared to not using NIV, although overall hospital mortality differences were not statistically significant.
- In intensive care settings, NIV significantly lowered mortality rates, demonstrating its effectiveness, especially among patients with overlapping conditions like COPD.
- The results suggest that NIV should be considered in treatment guidelines for pneumonia-related respiratory failure due to its substantial benefits in critical care outcomes.
Antagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (T) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect. TRPV1 can be activated by capsaicin (CAP), protons (low pH), and heat. First-generation (polymodal) TRPV1 antagonists potently block all three TRPV1 activation modes.
View Article and Find Full Text PDFIn pediatric burns the use of systemic antibiotic prophylaxis is a standard procedure in some burn centers, though its beneficial effect on the infectious complications is debated. The present meta-analysis aimed at determining whether systemic antibiotic prophylaxis prevents infectious complications in pediatric patients with burn injuries. We searched the PubMed, EMBASE, and Cochrane Library databases from inception to August 2019.
View Article and Find Full Text PDFRationale: Burns is a common type of traumatic injury in childhood. Nowadays, several wound dressings are available to treat the second-degree hand burns conservatively.
Patient Concerns, Diagnoses: At the authors' institute, 37 children were treated conservatively with a special dressing at first intervention containing Aquacel Ag foam and Zn-hyaluronic gel to determine their effectiveness on partial thickness hand burns.