Publications by authors named "Alexandra Clarke"

Article Synopsis
  • Food allergies are becoming more common, so it's crucial for hospitals to effectively identify and manage them to ensure patient safety.
  • A study involved interviews and surveys with hospital patients who have food allergies to assess their understanding and expectations regarding hospital food services.
  • Key findings revealed that while patients felt comfortable declaring their allergies and were satisfied with hospital food, further research is needed to pinpoint what factors are most important to them in their meals.
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Youth with craniofacial conditions often have appearance and speech differences and are vulnerable to social stigmatization and body image disturbances. Given sociocultural pressures for female attractiveness, adolescent girls with craniofacial conditions may be especially vulnerable to body dissatisfaction and appearance-related social stigmatization, though such sex differences have been infrequently studied in this population. This study aimed to: (1) examine sex differences in body image disturbance, satisfaction with speech and facial appearance, and perceived stigmatization among adolescents with craniofacial conditions; and (2) evaluate whether stigmatization perceptions are predictive of body image disturbance and satisfaction with facial appearance and speech.

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is a multidrug-resistant yeast which has emerged in health care facilities worldwide; however, little is known about identification methods, patient colonization, environmental survival, spread, and drug resistance. Colonization on both biotic (patients) and abiotic (health care objects) surfaces, along with travel, appear to be the major factors for the spread of this pathogen across the globe. In this investigation, we present laboratory findings from an ongoing outbreak in New York (NY) from August 2016 through 2018.

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The association between disfigurement ('visible difference') and romantic relationships has received relatively little consideration in the research literature. This qualitative research, conducted in the United Kingdom, explored participants' accounts of their visible difference and romantic life. Semi-structured interviews were conducted with 22 participants who had a variety of visible differences.

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Objective: To evaluate body image in adolescents with and without craniofacial conditions and to examine relationships between body image and quality of life.

Design: Case-control design.

Setting: A pediatric hospital's craniofacial center and primary care practices.

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Objectives: Strategies for oxygen therapy for preterm infants, such as the Vermont-Oxford's 'Breathsavers' guidelines, seek to strike a balance between the potential risks of the extremes of hyperoxia and hypoxia in preterm infants. Using an algorithm based on those guidelines, we aimed to compare the proportion of time spent within the SpO2 target range during algorithm-based management of oxygen delivery compared with routine nursing care.

Study Design: In a randomised crossover trial, maintenance of SpO2 over a 4-hour period during routine care was compared with algorithm-based control (administered by a dedicated research nurse).

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Article Synopsis
  • The study investigates how social inequalities at both the individual and community levels impact functional disability in patients with early inflammatory polyarthritis over a three-year period.
  • Researchers analyzed data from 1,393 patients, examining the relationship between their health outcomes (measured by the Health Assessment Questionnaire) and their socioeconomic status, determined by area deprivation and personal social class.
  • Results show that individuals from more deprived areas and lower social classes experienced worse health outcomes, suggesting that both personal circumstances and residential environment independently affect the progression of the disease.
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Objective: To assess immunologically relevant outcomes in a cohort of rheumatoid arthritis (RA) patients with prolonged therapy-induced lymphopenia.

Methods: Morbidity (infection or malignancy) and mortality were assessed in 53 RA patients who were treated with the lymphocytotoxic monoclonal antibody alemtuzumab between 1991 and 1994. Data were obtained by interview, medical record review, and Office for National Statistics mortality monitoring.

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Background: Primary care consultation data are an important source of information on morbidity prevalence. It is not known how reliable such figures are.

Aim: To compare annual consultation prevalence estimates for musculoskeletal conditions derived from four general practice consultation databases.

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Objective: Renal involvement is a major complication of systemic lupus erythematosus (SLE) and is a strong determinant of morbidity and mortality. There have been no previous studies of the epidemiology of lupus nephritis. Our aim was to establish the prevalence and incidence of biopsy-proven lupus nephritis in the northwest of England in 2001 and to examine the influence of age, sex, and ethnicity.

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