Single unmodified biomolecules in solution can be observed and characterized by interferometric imaging approaches; however, Rayleigh scattering limits this to larger proteins (typically >30 kDa). We observe real-time image tracking of unmodified proteins down to 14 kDa using interference imaging enhanced by surface plasmons launched at an aperture in a metal film. The larger proteins show slower diffusion, quantified by tracking.
View Article and Find Full Text PDFJ Med Imaging (Bellingham)
January 2021
: Prosthetic heart valve designs must be rigorously tested using cardiovascular equipment. The valve orifice area over time constitutes a key quality metric which is typically assessed manually, thus a tedious and error-prone task. From a computer vision viewpoint, a major unsolved issue lies in the orifice being partly occluded by the leaflets' inner side or inaccurately depicted due to its transparency.
View Article and Find Full Text PDFUnderwater images are often acquired in sub-optimal lighting conditions, in particular at profound depths where the absence of natural light demands the use of artificial lighting. Low-lighting images impose a challenge for both manual and automated analysis, since regions of interest can have low visibility. A new framework capable of significantly enhancing these images is proposed in this article.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
August 2012
This paper describes a novel algorithm for tracking the motion of the urethra from trans-perineal ultrasound. Our work is based on the structure-from-motion paradigm and therefore handles well structures with ill-defined and partially missing boundaries. The proposed approach is particularly well-suited for video sequences of low resolution and variable levels of blurriness introduced by anatomical motion of variable speed.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
March 2011
This paper proposes a new method for the automatic contrast enhancement of fiducial markers in low-radiation Electronic Portal Images. It is shown that the proposed approach significantly enhances the contrast of the fiducial markers and produces results where these markers are clearly visible. The main theoretical contribution consists in designing an algorithm that enhances the contrast of small structures in noisy images; the parameters of this algorithm are not empirically selected, but determined via a maximum search over a contrast metric.
View Article and Find Full Text PDFThis paper proposes a new morphology-based approach for the interslice interpolation of current transformer (CT) and MRI datasets composed of parallel slices. Our approach is object based and accepts as input data binary slices belonging to the same anatomical structure. Such slices may contain one or more regions, since topological changes between two adjacent slices may occur.
View Article and Find Full Text PDFWe propose a web-based collaborative CAD system allowing for the remote communication and data exchange between radiologists and researchers in computer vision-based software engineering. The proposed web-based interface is implemented in the Java Advanced Imaging Application Programming Interface. The different modules of the interface allow for 3D and 2D data visualization, as well as for the parametric adjustment of 3D reconstruction process.
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