Regulation of carbohydrate metabolism by nitric oxide and hydrogen sulfide: Implications in diabetes.

Nitric oxide (NO) and hydrogen sulfide (HS) are two gasotransmitters that are produced in the human body and have a key role in many of the physiological activities of the various organ systems. Decreased NO bioavailability and deficiency of HS are involved in the pathophysiology of type 2 diabetes and its complications. Restoration of NO levels have favorable metabolic effects in diabetes.