Publications by authors named "Alexandra Alves Duarte"
Article Synopsis
- Breast cancer is made up of various subtypes with different genetic and clinical characteristics, which this study highlights by detailing a method for long-term culturing of human mammary epithelial organoids.
- Over 100 organoid lines were created from primary and metastatic breast cancer, effectively mirroring the original tumors' features like histopathology and hormone receptor status.
- The organoids were also shown to maintain genetic consistency and allow for drug testing that corresponds well with actual patient outcomes, making them valuable for cancer research and personalized treatment strategies.
