Publications by authors named "Alexandra Abruzzo"

Article Synopsis
  • Pulmonary hypertension (PH) increases blood pressure in pulmonary arteries, leading to serious complications like low oxygen delivery, and this study examines its effects on patients with congestive heart failure after a heart attack (STEMI).
  • Researchers analyzed data from nearly 27,000 STEMI patients (with 95 having group II PH) to evaluate mortality rates and other health outcomes using the National Inpatient Sample database from 2017 to 2020.
  • The findings indicated that patients with GIIPH had significantly higher in-hospital mortality rates and longer hospital stays compared to those without PH, underscoring the negative impact of GIIPH on health and economic outcomes.
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Extracorporeal membrane oxygenation (ECMO) is a form of prolonged mechanical cardiopulmonary supportive therapy implemented for the survival of patients with refractory cardiac and respiratory dysfunction. Venovenous (VV) and venoarterial (VA) ECMO are both used to buy time in severe respiratory failure while VA ECMO also provides hemodynamic support. Unfortunately, the risk of developing circuit or cannula associated and systemic thrombosis in patients supported by ECMO and post circuit decannulation is a devastating complication, although the relationship between venous thromboembolism (VTE) and ECMO use has not been fully established.

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Carotid artery calcification (CAC) is a well-known marker of atherosclerosis and is linked to a high rate of morbidity and mortality. CAC is divided into two types: intimal and medial calcifications, each with its own set of risk factors. Vascular calcification is now understood to be an active, enzymatically regulated process involving dystrophic calcification and endothelial dysfunction at an early stage.

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