Publications by authors named "Alexander Zambidis"
Article Synopsis
- The study looked at a protein called TSPO that helps move cholesterol in mitochondria, and Atriol is a substance that can stop TSPO from binding to cholesterol.
- Researchers found that Atriol can help improve a liver disease called MASH by fixing mitochondrial function and reducing inflammation.
- In tests on rats with MASH, Atriol helped reduce fat buildup, inflammation, and other harmful effects, showing it might be a helpful treatment for this liver condition.
Mitochondrial membrane protein ATAD3A is a member of the AAA-domain-containing ATPases superfamily. It is important for the maintenance of mitochondrial DNA, structure, and function. In recent years, an increasing number of mutations have been identified in patients with neurological symptoms.
View Article and Find Full Text PDFThe objective of the study was to estimate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence in the Howard County, Maryland, general population and demographic subpopulations attributable to natural infection or coronavirus disease 2019 (COVID-19) vaccination and to identify self-reported social behaviors that may affect the likelihood of recent or past SARS-CoV-2 infection. A cross-sectional, saliva-based serological study of 2,880 residents of Howard County, Maryland, was carried out from July through September 2021. Natural SARS-CoV-2 infection prevalence was estimated by inferring infections among individuals according to anti-nucleocapsid immunoglobin G levels and calculating averages weighted by sample proportions of various demographics.
View Article and Find Full Text PDF