Publications by authors named "Alexander Yakovlev"

Article Synopsis
  • * Research indicates that exposure to psychoactive substances affects the production and composition of sEVs, with potential differences based on sex.
  • * The study suggests there are two mechanisms through which psychoactive substances impact sEVs: a "fast" mechanism that promotes neuroplasticity, and a "slow" mechanism that disrupts the normal production of sEVs.
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Background: Fibromyalgia (FM) is a chronic pain syndrome associated with significant distress and numerous unpleasant consequences. Mental health problems in people with FM have been reported in many studies. People with mental disorders are thought to be at higher risk of FM than the general population, but the prevalence has not been established.

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Article Synopsis
  • * A study in Russia examined 574 hospitalized children under 18 with COVID-19 from January 2022 to March 2023, finding about one-third had coinfections, predominantly adenovirus and bacterial infections.
  • * Results indicated that while viral coinfections led to higher fevers and bronchitis, bacterial coinfections resulted in longer illnesses and increased pneumonia, suggesting that seasonal viruses may have been more harmful to children during the Omicron wave than SARS-CoV-2 alone.
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An electromagnetic cloaking approach is employed with the intention to curb the destructive effects of mutual interference for rectangular and circularly shaped patch antennas situated in a tight spacing. Primarily, we show that by coating the top surface of each patch with an appropriately designed metasurface, the mutual coupling is considerably reduced between the antennas. Furthermore, the cloak construct is extended to a tightly spaced, interleaved linear patch antenna array configuration and it is shown that the coated metasurfaces successfully enhance the performance of each array in terms of their matching characteristics, total efficiencies and far-field realized gain patterns for a broad range of beam-scan angles.

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Objective: We hypothesized that PWE have an increased risk to acquire COVID-19. This was a historical cohort study to determine COVID-19 incidence, severity, mortality and risk factors in adults with active epilepsy (PWE) compared to residents of Moscow without epilepsy matched by age, gender, and region of residence - Moscow Community Comparisons (MCC).

Methods: Subjects were derived from a cohort of adult PWE and a cohort of age- and gender-matched population-based MCC without epilepsy identified in 2018.

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We have proposed an effective metasurface design to accomplish the cloaking of equilateral patch antennas and their array configuration. As such, we have exploited the concept of , employing the mantle cloaking technique with the intention to eliminate the destructive interference ensuing between two distinct triangular patches situated in a very congested arrangement (sub-wavelength separation is maintained between the patch elements). Based on the numerous simulation results, we demonstrate that the implementation of the planar coated metasurface cloaks onto the patch antenna surfaces compels them to become to each other, at the intended frequencies.

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Number of studies devoted to investigation of neuronal exosomes increases significantly each year. Potential of exosomes as diagnostic markers of neurodegenerative diseases has been examined thoroughly and similar protocols were used to search for the markers of other psychiatric disorders. Biogenesis of exosomes in various types of cells has been studied, physiological role of exosomes has been actively investigated, and many features of their signaling cascades have been clarified.

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The have introduced a new dimensional approach to personality disorder (PD) classification that relies on the global level of PD severity and individual expressions of personality dysfunction in terms of specified trait domains (i.e., negative affectivity, detachment, antagonism, disinhibition, anankastia, and psychoticism).

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In this work, we presented data from a two-year study of flavi-, flavi-like, and phenuiviruses circulation in the population of ixodid ticks in the Chelyabinsk region. We isolated three tick-borne encephalitis virus (TBEV) strains from , which was not detected in the ticks of the genus . The virus prevalence ranged from 0.

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Neuropsychiatric complications, in particular cognitive and depressive disorders, are common consequences of ischemic stroke (IS) and complicate the rehabilitation, quality of life, and social adaptation of patients. The hypothalamic-pituitary-adrenal (HPA) system, sympathoadrenal medullary system (SAMS), and inflammatory processes are believed to be involved in the pathogenesis of these disorders. This study aimed to explore these systems in IS patients, including those with post-stroke cognitive and depressive disorders, within a year after IS.

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Background: The hypothalamic-pituitary-adrenal (HPA) axis, inflammatory processes and neurotrophic factor systems are involved in pathogenesis of both epilepsy and depressive disorders. The study aimed to explore these systems in patients with focal epilepsy (PWE, = 76), epilepsy and comorbid depression (PWCED = 48), and major depressive disorder (PWMDD, = 62) compared with healthy controls (HC, = 78).

Methods: Parameters of the HPA axis, neurotrophic factors, and TNF-α were measured in blood serum along with the hemogram.

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Background: Vaccine hesitancy causes serious difficulties in vaccination campaigns in many countries. The study of the population's attitude toward vaccination and detection of the predictive important individual psychological and social factors defining the vaccination necessity perception will allow elaborating promoting vaccination adherence measures.

Objectives: The aim of this research was to study COVID-19 threat appraisal, fear of COVID-19, trust in COVID-19 information sources, COVID-19 conspiracy beliefs, and the relationship of sociodemographic variables to COVID-19 preventive behavior.

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Objective: To develop a Russian version of The Epilepsy Anxiety Survey Instrument (EASI) and assess its psychometric properties in a Russian sample of patients with epilepsy (PWE). To compare the brief version of EASI with the General Anxiety Disorder-7 (GAD-7) - the most common tool for a rapid anxiety screening.

Methods: The study sample consisted of 181 consecutive Russian-speaking PWE.

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Objectives: This study aimed to estimate the impact of the COVID-19 pandemic on the circulation of non-SARS-CoV-2 respiratory viruses and the clinical characteristics of COVID-19 in hospitalized children.

Methods: A total of 226 and 864 children admitted to the Children's City Clinical Hospital with acute respiratory infection in September to November of 2018 and 2020 in Moscow were tested for respiratory viruses using multiplex polymerase chain reaction (PCR) and Mycoplasma pneumoniae/Chlamydia pneumoniae using enzyme-linked immunosorbent assay.

Results: The detection rate of non-SARS-CoV-2 viruses in 2020 was lower than in 2018, 16.

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This work studies the propagation characteristics of a rectangular waveguide with aligned/misaligned double-sided dielectric-filled metallic corrugations. Two modes are found to propagate in the proposed double-sided configuration below the hollow-waveguide cutoff frequency: a quasi-resonant mode and a backward mode. This is in contrast to the single-sided configuration, which only allows for backward propagation.

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Objective: To assess the capacity of Generalized Anxiety Disorder-7 (GAD-7) to detect anxiety disorders in a Russian sample of patients with epilepsy and to validate this instrument for rapid screening of anxiety in these patients.

Methods: Study included 233 patients with epilepsy, both inpatients and outpatients. For all patients Mini-International Neuropsychiatric Interview was conducted as a gold standard for diagnosis of mental disorders.

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Article Synopsis
  • The study aimed to explore Interictal Dysphoric Disorder (IDD) in individuals with epilepsy and major depressive disorder (MDD) compared to those with MDD but no neurological conditions, challenging the idea that IDD is exclusive to epilepsy patients.
  • Researchers analyzed data from 142 epilepsy patients and 222 controls, using various psychological assessments to evaluate the prevalence and characteristics of IDD, finding no significant differences between the two groups.
  • The results indicated that IDD symptoms were similar in both groups, and while individuals with IDD experienced longer durations of affective disorders, the presence of epilepsy did not significantly correlate with IDD symptoms.
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