Publications by authors named "Alexander Y P Chan"

Objectives: To determine whether individualised manual therapy plus guideline-based advice results in superior outcomes to advice alone in participants with clinical features potentially indicative of lumbar zygapophyseal joint pain.

Design: Multi centre parallel group randomised controlled trial.

Setting: 14 physiotherapy clinics in Melbourne, Australia.

View Article and Find Full Text PDF

Objective: To identify predictors for back pain, leg pain, and activity limitation in patients with early persistent low back disorders (LBDs).

Design: Prospective inception cohort study.

Setting: Primary care private physiotherapy clinics in Melbourne, Australia.

View Article and Find Full Text PDF

Study Design: A preplanned effect modifier analysis of the Specific Treatment of Problems of the Spine randomized controlled trial.

Objective: To identify characteristics associated with larger or smaller treatment effects in people with low back disorders undergoing either individualized physical therapy or guideline-based advice.

Summary Of Background Data: Identifying subgroups of people who attain a larger or smaller benefit from particular treatments has been identified as a high research priority for low back disorders.

View Article and Find Full Text PDF

Objectives: To evaluate the effectiveness of individualised functional restoration plus guideline-based advice compared to advice alone in people with non-reducible discogenic pain (NRDP).

Design: Subgroup analysis within a multicentre, parallel group randomised controlled trial.

Setting: Fifteen primary care physiotherapy clinics.

View Article and Find Full Text PDF

Background Context: Physical therapy is commonly sought by people with lumbar disc herniation and associated radiculopathy. It is unclear whether physical therapy is effective for this population.

Purpose: To determine the effectiveness of physical therapist-delivered individualized functional restoration as an adjunct to guideline-based advice in people with lumbar disc herniation and associated radiculopathy.

View Article and Find Full Text PDF

Background: Low back disorders are prevalent and directional preference management is a common treatment with mixed evidence for effectiveness.

Objectives: To determine the effectiveness of individualised directional preference management plus guideline-based advice versus advice alone in participants with reducible discogenic pain of 6-week to 6-month duration.

Design: Pre-planned secondary analysis of a multicentre, parallel group randomised controlled trial.

View Article and Find Full Text PDF

Study Design: A cost-utility analysis within a randomized controlled trial was conducted from the health care perspective.

Objective: The aim of this study was to determine whether individualized physical therapy incorporating advice is cost-effective relative to guideline-based advice alone for people with low back pain and/or referred leg pain (≥6 weeks, ≤6 months duration of symptoms).

Summary Of Background Data: Low back disorders are a burdensome and costly condition across the world.

View Article and Find Full Text PDF
Article Synopsis
  • The study examines the effectiveness of individualized physiotherapy combined with guideline-based advice compared to just advice alone for patients with low-back disorders lasting more than 6 weeks.
  • Conducted in Melbourne, Australia, the trial involved 300 participants, with 156 receiving personalized physiotherapy treatment and 144 receiving only advice over varying time points.
  • Results indicated that those who received individualized physiotherapy experienced significantly better outcomes in pain relief and functional improvement at multiple follow-ups, demonstrating a higher likelihood of achieving clinical improvement over time.
View Article and Find Full Text PDF

Background: Low back disorders are a common and costly cause of pain and activity limitation in adults. Few treatment options have demonstrated clinically meaningful benefits apart from advice which is recommended in all international guidelines. Clinical heterogeneity of participants in clinical trials is hypothesised as reducing the likelihood of demonstrating treatment effects, and sampling of more homogenous subgroups is recommended.

View Article and Find Full Text PDF