Publications by authors named "Alexander W R Burns"

Background: Intravenous antibiotic infusion has been the standard prophylaxis for total joint arthroplasty surgery. However, infection rates still occur at 1%-2% in many series. Single-dose intra-articular antibiotics (IAAs) present a safe and potentially more effective prophylactic regime in total joint arthroplasty.

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Background: The use of a single dose of intra-articular antibiotic (IAA) has been reported in reducing the rate of prosthetic joint injection after total hip and knee arthroplasty. We examine the safety of IAA in primary hip and knee replacement surgery and the blood levels and joint fluid levels of vancomycin utilising this technique.

Methods: From August to October 2021, 68 patients undergoing primary total joint arthroplasty (THA & TKA) were given 1g vancomycin intra-articularly (IA)after closure of the fascia.

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Article Synopsis
  • * The study compares the effectiveness of aspirin versus enoxaparin in reducing 90-day mortality for patients after hip or knee arthroplasties, part of a larger trial conducted in 31 Australian hospitals.
  • * After analyzing 23,458 patients, the results aim to determine if there is a significant difference in 90-day mortality rates between those taking aspirin and those on enoxaparin.
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Article Synopsis
  • There is a noted gap in research regarding the effectiveness of aspirin alone for preventing symptomatic venous thromboembolism (VTE) following total hip or knee surgeries, prompting this study.
  • The objective was to compare the effectiveness of aspirin versus enoxaparin in reducing instances of symptomatic VTE after these surgeries, using a large cluster-randomized trial involving over 9,700 patients in Australia.
  • The study found that the trial was stopped early after interim results indicated that aspirin was noninferior to enoxaparin in preventing VTE, with a focus on patient outcomes such as pulmonary embolism, deep vein thrombosis, and other complications within 90 days post-surgery.
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As the numbers of arthroplasties performed worldwide increase, so do complications such as prosthetic joint infection. Cases that require a two-stage revision of a total femur replacement in the femur pose an ongoing challenge to the modern orthopedic surgeon. Unlike antibiotic spacers in hip and knee arthroplasty, there lacks a commercially available cement spacer for use in total femur replacements.

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Introduction: Soft tissue imbalance is considered to be a major surgical cause of dissatisfaction following total knee arthroplasty (TKA). Surgeon-determined manual assessment of ligament tension has been shown to be a poor determinant of the true knee balance state. The recent introduction of intraoperative sensors, however, allows surgeons to precisely quantify knee compartment pressures and tibiofemoral kinematics, thereby optimising coronal and sagittal plane soft tissue balance.

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Article Synopsis
  • The study investigates the rising rates of arthroscopic surgery for femoroacetabular impingement (FAI) and aims to identify if the size and location of deformities can predict patient outcomes post-surgery.
  • It analyzed CT surgical plans of 90 hips from 79 patients and assessed various morphological parameters related to the femur and acetabulum in order to correlate them with patient hip scores before and after surgery.
  • Findings reveal that a greater volume of cam deformity is linked to worse postoperative outcomes, while the morphological factors did not predict preoperative scores or overall surgical improvement.
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Unlabelled: Total knee arthroplasty now exceeds total hip arthroplasty as the most commonly performed joint replacement. Projections suggest the need for revision knee arthroplasty in the future will produce an immense economic burden. The excellent cost effectiveness of primary knee arthroplasty has been well established.

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