Publications by authors named "Alexander Thesleff"

Highly impaired individuals stand to benefit greatly from cutting-edge bionic technology, however concurrent functional deficits may complicate the adaptation of such technology. Here, we present a case in which a visually impaired individual with bilateral burn injury amputation was provided with a novel transradial neuromusculoskeletal prosthesis comprising skeletal attachment via osseointegration and implanted electrodes in nerves and muscles for control and sensory feedback. Difficulties maintaining implant hygiene and donning and doffing the prosthesis arose due to his contralateral amputation, ipsilateral eye loss, and contralateral impaired vision necessitating continuous adaptations to the electromechanical interface.

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Most amputations occur in lower limbs and despite improvements in prosthetic technology, no commercially available prosthetic leg uses electromyography (EMG) information as an input for control. Efforts to integrate EMG signals as part of the control strategy have increased in the last decade. In this systematic review, we summarize the research in the field of lower limb prosthetic control using EMG.

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Skeletal attachment of limb prostheses ensures load transfer between the prosthetic leg and the skeleton. For individuals with lower limb amputation, these loads may be of substantial magnitude. To optimize the design of such systems, knowledge about the structural interplay between implant design features, dimensional changes, and material properties of the implant and the surrounding bone is needed.

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Article Synopsis
  • Fretting fatigue is a significant issue for modular orthopedic implants, leading to possible mechanical failure and inflammation due to wear debris.
  • A study examined how low plasticity burnishing (LPB), a surface enhancement method, can improve the resistance of these implants to fretting fatigue.
  • Results showed LPB-treated specimens can endure significantly more load cycles (over 108,000) compared to untreated ones (just under 38,000), suggesting LPB can reduce wear and the need for implant revisions.
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The development of control algorithms and prosthetic hardware for lower limb prostheses involves an iterative testing process. Here, we present the design and validation of a bypass socket to enable able-bodied researchers to wear a leg prosthesis for evaluation purposes. The bypass socket can be made using a 3D-printer and standard household tools.

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In research on lower limb prostheses, safety during testing and training is paramount. Lower limb prosthesis users risk unintentional loss of balance that can result in injury, fear of falling, and overall decreased confidence in their prosthetic leg. Here, we present a protocol for managing the risks during evaluation of active prosthetic legs with modifiable control systems.

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Direct skeletal attachment of lower limb prostheses ensures direct load transfer between the prosthetic leg and the skeleton. Knowledge of the load characteristics at the boneimplant interface during high-loading activities is needed to understand the limitations of current implant systems, as well as to inform their future development. The present study estimates the load scenario at the bone-implant interface of a transfemoral amputee while running with kinematic symmetry between the prosthetic and the intact limbs corresponding to that of an ablebodied subject.

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Bone-anchored limb prostheses allow for the direct transfer of external loads from the prosthesis to the skeleton, eliminating the need for a socket and the associated problems of poor fit, discomfort, and limited range of movement. A percutaneous implant system for direct skeletal attachment of an external limb must provide a long-term, mechanically stable interface to the bone, along with an infection barrier to the external environment. In addition, the mechanical integrity of the implant system and bone must be preserved despite constant stresses induced by the limb prosthesis.

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